Yes! The constitution of The United States is an aging document from the past no different than a holy book one can find. Both are frozen snapshots in time subject to being proven inaccurate or wrong as a function of the changing of time. People who do not want our constitution to change are like stubborn theologists who, despite ample evidence to the contrary, refute the undeniable and incredible discoveries we categorize as science, better known as the study of nature.
For its time, the constitution was a remarkable achievement and contained incredible fundamentals of foresight other countries in the world should adopt. For example, the separation of church and state clause in the first amendment, as the only country in the world that clearly and unequivocally separates them, comes to mind as the essential guide to the formation of a responsible immigration policy much needed today. We should be in awe of the incredible foresight our founding fathers instilled in the constitution, and how far in time it reached and remained relevant.
Despite such incredible foresight, the excellence by which we interpreted and executed on the constitution leaves a lot to be desired today. The imperfection of any theory will be eroded by the test of time, causing it to first reform downstream (using amendments) until we discover the root-cause by which a constitutional rule or right is wrong, upon which upstream reform of the causal theory is required. Similar upstream reform from Einstein comes to mind in the reinvention of much-lauded prior assumptions in science.
Concerning the constitution, the desire for freedom, for example, described by the rulings in the constitution, has yielded an implementation of freedom that is utterly flawed. Today, all of our economic systems (including capitalism) in compliance with the constitution fail the most basic litmus test that enables equal freedom to all participants—demonstrating that the consequential actions of a constitution can prove the causal rule wrong or absent.
So, apart from continual downstream reform to the constitution, upstream reform to the constitution is needed at times for us to function to the best of our ability. Our constitution should be a living document of both downstream and upstream reform that reflects at all times the morals we hold in high regard.